Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870833 | 1.00 | CASR (0.36) | CASRHSD17B10CA12CA2CA9 | |
| SCHEMBL8871677 | 0.92 | NPC1 (0.38) | CASRHSD17B10CA12CA2CA9 | |
| SCHEMBL8871681 | 0.92 | NPC1 (0.38) | CASRHSD17B10CA12CA2CA9 | |
| SCHEMBL8870479 | 0.91 | HTT (0.45) | CASRNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8870489 | 0.91 | HTT (0.45) | CASRNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8870433 | 0.90 | NPC1 (0.41) | CASRHSD17B10CA12CA2CA9 | |
| SCHEMBL8870431 | 0.90 | NPC1 (0.41) | CASRHSD17B10CA12CA2CA9 | |
| SCHEMBL8870544 | 0.90 | NPC1 (0.41) | CASRHSD17B10CA12CA2CA9 | |
| SCHEMBL5276625 | 0.90 | MEN1 (0.42) | CASRHSD17B10CA12CA2CA9 | |
| SCHEMBL7572233 | 0.90 | MEN1 (0.42) | CASRHSD17B10CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |