Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31289648 | 1.00 | DPP4 (0.47) | DPP4KCNH2SCN3ATP53L3MBTL1 | |
| SCHEMBL31289649 | 1.00 | DPP4 (0.47) | DPP4KCNH2SCN3ATP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL31289646 | 0.98 | DPP4 (0.46) | DPP4KCNH2SCN3ATP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8871065 | 0.98 | DPP4 (0.46) | DPP4KCNH2SCN3ATP53L3MBTL1 | |
| SCHEMBL28308179 | 0.89 | DPP4 (0.47) | DPP4KCNH2SCN3ATP53L3MBTL1 | |
| SCHEMBL135105 | 0.89 | KCNH2 (0.56) | DPP4KCNH2SCN3AAKR1C3AKR1C1 | |
| SCHEMBL1226045 | 0.89 | KCNH2 (0.56) | DPP4KCNH2SCN3AAKR1C3AKR1C1 | |
| SCHEMBL135106 | 0.89 | KCNH2 (0.56) | DPP4KCNH2SCN3AAKR1C3AKR1C1 | |
| SCHEMBL8513273 | 0.89 | KCNH2 (0.56) | DPP4KCNH2SCN3AAKR1C3AKR1C1 | |
| SCHEMBL197425 | 0.89 | KCNH2 (0.56) | DPP4KCNH2SCN3AAKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |