Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871099 | 1.00 | PTAFR (0.40) | PTAFRTSHRPRMT3TBXAS1 | |
| SCHEMBL7572233 | 0.91 | MEN1 (0.42) | — | |
| SCHEMBL5276625 | 0.91 | MEN1 (0.42) | — | |
| SCHEMBL8870865 | 0.90 | CA12 (0.38) | — | |
| SCHEMBL8870863 | 0.90 | CA12 (0.38) | — | |
| SCHEMBL8870861 | 0.89 | CNR1 (0.42) | — | |
| SCHEMBL8870858 | 0.89 | CNR1 (0.42) | — | |
| SCHEMBL8871337 | 0.89 | NPC1 (0.46) | — | |
| SCHEMBL8871339 | 0.89 | NPC1 (0.46) | — | |
| SCHEMBL8871351 | 0.87 | EPHX2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |