Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | POLG | P54098 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516266 | 0.94 | POLB (0.38) | POLBLMNAP2RY2P2RY4CACNA1F | |
| SCHEMBL8491773 | 0.92 | POLB (0.45) | POLBLMNAP2RY2P2RY4CACNA1F | |
| SCHEMBL7199260 | 0.88 | POLB (0.41) | POLBLMNAP2RY2P2RY4CACNA1F | |
| SCHEMBL5859682 | 0.88 | POLB (0.41) | POLBLMNAP2RY2P2RY4CACNA1F | |
| SCHEMBL2112368 | 0.86 | POLB (0.42) | POLBP2RY2P2RY4MAPTP2RY6 | |
| SCHEMBL618137 | 0.86 | POLB (0.39) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL7533550 | 0.85 | POLB (0.51) | POLBP2RY6NT5E | |
| SCHEMBL2270354 | 0.85 | POLB (0.38) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL332975 | 0.85 | POLB (0.51) | POLBP2RY6NT5E | |
| SCHEMBL8607542 | 0.85 | POLB (0.49) | POLBLMNAMAPTP2RY6NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107473972-B | Nucleoside protective group and preparation thereof | 上海兆维科技发展有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-109232692-A | A kind of deoxycytidine class organic synthesis intermediate and preparation method thereof | 中国医学科学院放射医学研究所 | 2019-01-18 | — | — | CN | disclosed |
| EP-2399611-A2 | Use of an oligonucleotide or its active derivative for the preparation of a pharmaceutical composition for inhibiting the formation of metasatases in cancer treatment | Antisense Pharma GmbH (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-6596537-B1 | Oligonucleotide for use in the treatment of cancer, infections and autoimmune diseases | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-0119621-A1 | Interleukin-2 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-09-26 | — | — | EP | disclosed |
| EP-0040099-A1 | Polynucleotide synthesis | ens BIO LOGICALS INC. (CA) | 1981-11-18 | — | — | EP | disclosed |