Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886414 | 0.84 | PTGDR2 (0.60) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL13739997 | 0.84 | PTGDR2 (0.60) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL8871466 | 0.83 | PTGDR2 (0.66) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL8869916 | 0.82 | NPC1 (0.52) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL8871046 | 0.81 | MAPT (0.67) | KDM4ELMNAPOLBNPSR1MAPT | |
| SCHEMBL13739123 | 0.81 | KDM4E (0.61) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL19901062 | 0.81 | NPC1 (0.51) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL9951654 | 0.81 | MEN1 (0.62) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL25869080 | 0.81 | MEN1 (0.61) | PTGDR2KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL10029548 | 0.80 | MEN1 (0.65) | PTGDR2KDM4ELMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646164-A | FOR THE TREATMENT OR PREVENTION OF CARDIOVASCULAR DISEASE | NATIONAL SCIENCE COUNCIL (TW) | 1997-07-08 | — | — | US | disclosed |