Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272780 | 0.86 | CA12 (0.57) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL18395594 | 0.82 | KDM4E (0.55) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL210314 | 0.81 | POLB (0.63) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL7346296 | 0.81 | POLB (0.54) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL14833158 | 0.81 | HPGD (0.54) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL28533748 | 0.80 | HPGD (0.53) | POLBHPGDTYRDAOAKR1B1 | |
| Water SCHEMBL28341685 | 0.79 | POLB (0.61) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL4218836 | 0.78 | MAOB (0.54) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL7566904 | 0.78 | KDM4E (0.58) | POLBHPGDTYRDAOAKR1B1 | |
| SCHEMBL29625900 | 0.78 | KDM4E (0.50) | POLBHPGDTYRDAOAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646164-A | FOR THE TREATMENT OR PREVENTION OF CARDIOVASCULAR DISEASE | NATIONAL SCIENCE COUNCIL (TW) | 1997-07-08 | — | — | US | disclosed |