Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002356 | 0.92 | — | — | |
| SCHEMBL29000494 | 0.85 | PTGER4 (0.30) | PTGER4PTGER3PTGER2TSHRHIF1A | |
| SCHEMBL8671334 | 0.85 | PTGER4 (0.30) | PTGER4PTGER3PTGER2TSHRHIF1A | |
| SCHEMBL861890 | 0.83 | SMN1; SMN2 (0.39) | TSHR | |
| SCHEMBL29044933 | 0.81 | — | — | |
| SCHEMBL29120708 | 0.76 | TSHR (0.34) | TSHR | |
| SCHEMBL29176326 | 0.76 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL29031126 | 0.76 | MEN1 (0.37) | HIF1ALMNAALDH1A1 | |
| SCHEMBL28984897 | 0.75 | DPP4 (0.32) | — | |
| SCHEMBL4421431 | 0.74 | FFAR4 (0.31) | FFAR4FFAR1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405886-A1 | TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Isp Investments Inc. (US) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010105052-A1 | TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2010-09-16 | — | — | WO | disclosed |