Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261933 | 0.74 | PDE4A (0.44) | KDM4EPOLBALDH1A1HPGDMAPT | |
| SCHEMBL13255445 | 0.71 | PARP1 (0.46) | KDM4EALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL8874761 | 0.70 | SMN1; SMN2 (0.52) | KDM4EPOLBALDH1A1MAPTKMT2A | |
| SCHEMBL25647629 | 0.69 | PARP1 (0.49) | KDM4EHSD17B10TYMS | |
| SCHEMBL12237369 | 0.69 | PDE4A (0.61) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL1553062 | 0.69 | PDE4A (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL18643546 | 0.68 | TYMS (0.43) | KDM4EALDH1A1HPGDHSD17B10TYMS | |
| SCHEMBL527419 | 0.68 | PARP1 (0.60) | KDM4EALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL18643549 | 0.65 | PDE3B (0.64) | KDM4EHSD17B10TYMS | |
| SCHEMBL25414495 | 0.65 | PARP1 (0.48) | KDM4EGPR183ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639881-A | ANTITUMOR AGENTS, TREATMENT OF BREAST CANCER | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-06-17 | — | — | US | disclosed |