Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15931887 | 0.85 | HPGD (0.50) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL4551128 | 0.84 | PPARA (0.51) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL15932116 | 0.84 | CYP4F2 (0.47) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL15931948 | 0.83 | HPGD (0.46) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL15932107 | 0.83 | HPGD (0.46) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL11133950 | 0.83 | PPARA (0.53) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL15931414 | 0.82 | HPGD (0.58) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL20524093 | 0.82 | HPGD (0.45) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL15931828 | 0.82 | HPGD (0.45) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL15931827 | 0.82 | HPGD (0.45) | ALDH1A1HPGDHSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |