Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.32 |
| ▸ | RELA | Q04206 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875001 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8876063 | 0.89 | RARB (0.43) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8874662 | 0.89 | RARB (0.43) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8874657 | 0.89 | RARB (0.43) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8876070 | 0.89 | RARB (0.43) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8875177 | 0.89 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8875181 | 0.89 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8875134 | 0.88 | RARB (0.39) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL8875140 | 0.88 | RARB (0.39) | SMN1; SMN2MAPTRARBTHRBTHRA | |
| SCHEMBL9724235 | 0.88 | RARB (0.39) | SMN1; SMN2MAPTRARBTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641428-A | SHORT SWITCHING TIMES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |