Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | VHL | P40337 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 4/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436389 | 1.00 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8539204 | 1.00 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9666007 | 1.00 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9667987 | 1.00 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9667721 | 0.98 | MEN1 (0.42) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL1078939 | 0.92 | MEN1 (0.43) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL28037973 | 0.84 | — | — | |
| SCHEMBL9837049 | 0.81 | MEN1 (0.45) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705940 | 0.81 | MEN1 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL7424584 | 0.81 | VHL (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0207453-B1 | Heterocyclic substituted-phenoxyalkyl-isoxazoles and-furans, their preparation and use as antiviral agents | STERLING WINTHROP INC (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5175178-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| EP-0137242-B1 | (SUBSTITUTED) PHENYL-ALIPHATIC-ISOXAZOLES USEFUL AS ANTIVIRAL AGENTS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5051437-A | Treatment of rhinovirus or picornaviruses | STERLING DRUG INC. (US) | 1991-09-24 | — | — | US | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4945164-A | 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof | STERLING DRUG INC. (US) | 1990-07-31 | — | — | US | disclosed |
| US-4942241-A | PICORNAVIRUS INCLUDING RHINOVIRUS | STERLING DRUG INC. (US) | 1990-07-17 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4857539-A | Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents | STERLING DRUG INC. (US) | 1989-08-15 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |
| EP-0207453-A2 | Heterocyclic substituted-phenoxyalkyl-isoxazoles and-furans, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |
| EP-0137242-A2 | (Substituted) Phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof | STERLING WINTHROP INC. (US) | 1985-04-17 | — | — | EP | disclosed |