Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875598 | 1.00 | RARB (0.47) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8873490 | 0.90 | RARB (0.39) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8873483 | 0.90 | RARB (0.39) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8875835 | 0.89 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8873620 | 0.89 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8873928 | 0.89 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8873613 | 0.89 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8873917 | 0.89 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8874586 | 0.89 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8874580 | 0.89 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641428-A | SHORT SWITCHING TIMES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |