Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879687 | 0.91 | FABP3 (0.50) | FABP3FABP4FABP5GCGRDHODH | |
| SCHEMBL8880484 | 0.90 | DHODH (0.53) | FABP3FABP4FABP5GCGRDHODH | |
| SCHEMBL8879109 | 0.90 | FABP3 (0.49) | FABP3FABP4FABP5GCGRDHODH | |
| SCHEMBL8879628 | 0.88 | DHODH (0.55) | FABP3FABP4FABP5GCGRDHODH | |
| SCHEMBL2651071 | 0.84 | GCGR (0.56) | FABP3FABP4FABP5GCGR | |
| SCHEMBL10433875 | 0.82 | HMGCR (0.48) | FABP3FABP4FABP5GCGRDHODH | |
| SCHEMBL8875946 | 0.82 | FABP3 (0.60) | FABP3FABP4FABP5GCGRDHODH | |
| SCHEMBL5098308 | 0.81 | GCGR (0.50) | FABP3FABP4FABP5GCGR | |
| SCHEMBL27293870 | 0.80 | GCGR (0.49) | FABP3FABP4FABP5GCGR | |
| SCHEMBL8878602 | 0.79 | GCGR (0.64) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |