Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | KLK7 | P49862 | 8/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651006 | 0.75 | KDM1A (0.61) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL6072792 | 0.73 | NOTUM (0.46) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL7154077 | 0.69 | KDM1A (0.62) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL6649116 | 0.69 | KDM1A (0.62) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL16178518 | 0.67 | KDM1A (0.43) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL16178519 | 0.67 | KDM1A (0.43) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL16188078 | 0.67 | KDM1A (0.43) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL16188084 | 0.67 | KDM1A (0.43) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL16188058 | 0.67 | KDM1A (0.43) | KDM1ASCN9APDK2BCHENOTUM | |
| SCHEMBL6364363 | 0.67 | KDM1A (0.45) | KDM1ASCN9APDK2BCHENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696130-A | Tricyclic steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-09 | — | — | US | disclosed |
| US-5693646-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |