Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877162 | 1.00 | GAA (0.37) | GAAMAPTSCN9AJAK2CNR1 | |
| SCHEMBL8114104 | 0.87 | GAA (0.37) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8114102 | 0.87 | GAA (0.37) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8774817 | 0.87 | MAPT (0.39) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8774640 | 0.87 | MAPT (0.39) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8774808 | 0.87 | MAPT (0.39) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8774628 | 0.87 | MAPT (0.39) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8774340 | 0.85 | MAPT (0.38) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8774329 | 0.85 | MAPT (0.38) | GAAMAPTJAK2SPHK1CYP2C9 | |
| SCHEMBL8774638 | 0.82 | CYP2C9 (0.38) | GAAMAPTJAK2SPHK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629428-A | 3-Chloropyridines, and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-13 | — | — | US | disclosed |