Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879624 | 0.93 | GCGR (0.40) | GCGR | |
| SCHEMBL8876752 | 0.92 | GCGR (0.42) | GCGR | |
| SCHEMBL8876757 | 0.84 | GCGR (0.42) | GCGR | |
| SCHEMBL8877367 | 0.83 | HMGCR (0.47) | GCGR | |
| SCHEMBL8952827 | 0.83 | ESR1 (0.42) | GCGR | |
| SCHEMBL8952824 | 0.83 | ESR1 (0.42) | GCGR | |
| SCHEMBL8878307 | 0.80 | PRKAA2 (0.39) | — | |
| SCHEMBL8877126 | 0.79 | HMGCR (0.40) | — | |
| SCHEMBL8878123 | 0.76 | — | — | |
| SCHEMBL8952906 | 0.76 | GCGR (0.44) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |