Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878536 | 0.90 | GCGR (0.46) | GCGRHMGCRPTGS2 | |
| SCHEMBL8877859 | 0.89 | GCGR (0.45) | GCGRHMGCR | |
| SCHEMBL8879706 | 0.88 | GCGR (0.44) | GCGRHMGCR | |
| SCHEMBL8878254 | 0.85 | GCGR (0.51) | GCGRHMGCR | |
| SCHEMBL8877472 | 0.84 | GCGR (0.50) | GCGRHMGCR | |
| SCHEMBL8949603 | 0.81 | GCGR (0.58) | GCGR | |
| SCHEMBL8879109 | 0.80 | FABP3 (0.49) | GCGR | |
| SCHEMBL8321756 | 0.80 | GCGR (0.46) | GCGR | |
| SCHEMBL9562922 | 0.80 | HMGCR (0.56) | GCGRHMGCR | |
| SCHEMBL8950007 | 0.78 | GCGR (0.46) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |