Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12561239 | 0.83 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL932338 | 0.83 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1224654 | 0.83 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1549377 | 0.81 | — | — | |
| SCHEMBL8780916 | 0.79 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11246615 | 0.79 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Fluoromethane SCHEMBL28248919 | 0.79 | CYP1A2 (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21832 | 0.79 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2593140 | 0.79 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL28004207 | 0.78 | GAA (0.79) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5676831-A | ANXIOLYTIC AGENTS, ANTICONVULSANTS | RHONE-POULEC RORER S.A. (FR) | 1997-10-14 | — | — | US | disclosed |
| US-5599936-A | HYDRATION OF RACEMIC MIXTURE | RHONE-POUELNC RORER S.A. (FR) | 1997-02-04 | — | — | US | disclosed |
| US-5494915-A | RACEMIC MIXTURES AS MUSCLE RELAXANTS, ANXIOLYTIC, ANTIEPILEPTIC OR ANTICONVULSIVE AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-27 | — | — | US | disclosed |