Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.85 |
| ▸ | FNTB | P49356 | 6/20 | 0.85 |
| ▸ | SLC6A15 | Q9H2J7 | 11/20 | 0.76 |
| ▸ | HRH1 | P35367 | 6/20 | 0.76 |
| ▸ | PTAFR | P25105 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879257 | 0.94 | FNTA (0.89) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL8881143 | 0.92 | FNTA (0.85) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL8880256 | 0.91 | FNTA (0.78) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL31350768 | 0.91 | FNTA (0.78) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL8878143 | 0.89 | FNTA (0.78) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL8887709 | 0.89 | FNTA (0.80) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL16385870 | 0.88 | FNTA (0.73) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9139331 | 0.88 | FNTA (0.73) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL8879211 | 0.88 | FNTA (0.75) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL8877831 | 0.88 | FNTA (0.75) | FNTAFNTBSLC6A15HRH1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665726-A | ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0396083-B1 | Heterocyclic N-oxide derivatives of substituted benzo[5,6]cycloheptapyridines, compositions and methods of use | SCHERING CORP (US) | 1994-11-30 | — | — | EP | disclosed |
| EP-0471750-A1 | HETEROCYCLIC N-OXIDE DERIVATIVES OF SUBSTITUTED BENZO 5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1992-02-26 | — | — | EP | disclosed |
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| WO-1990013548-A1 | HETEROCYCLIC N-OXIDE DERIVATIVES OF SUBSTITUTED BENZO[5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1990-11-15 | — | — | WO | disclosed |
| EP-0396083-A1 | Heterocyclic N-oxide derivatives of substituted benzo[5,6]cycloheptapyridines, compositions and methods of use | SCHERING CORPORATION (US) | 1990-11-07 | — | — | EP | disclosed |