Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.61 |
| ▸ | PDE4A | P27815 | 16/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385992 | 1.00 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7786846 | 0.90 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7793134 | 0.90 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7472625 | 0.90 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7318584 | 0.89 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8879699 | 0.89 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7400233 | 0.88 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7400235 | 0.88 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7409643 | 0.87 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7786662 | 0.87 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602173-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-11 | — | — | US | claimed |
| US-5602173-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |