Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | CLK2 | P49760 | 1/20 | 0.63 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302438 | 1.00 | KCNH2 (0.70) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL8592629 | 1.00 | KCNH2 (0.70) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9231095 | 0.96 | KCNH2 (0.67) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9232519 | 0.93 | KCNH2 (0.70) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL8882435 | 0.93 | KCNH2 (0.59) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL8882612 | 0.91 | KCNH2 (0.62) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL8881581 | 0.91 | KCNH2 (0.62) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9232752 | 0.91 | KCNH2 (0.62) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL8882959 | 0.91 | KCNH2 (0.62) | KCNH2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL6488649 | 0.91 | KCNH2 (0.68) | KCNH2KDM4EHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677316-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | claimed |
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | claimed |
| US-5677316-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |