Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 8/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.63 |
| ▸ | HTR6 | P50406 | 9/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 5/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880277 | 1.00 | HTR1B (0.63) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8880280 | 1.00 | HTR1B (0.63) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8879963 | 0.97 | HTR1B (0.62) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8879970 | 0.97 | HTR1B (0.62) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8879378 | 0.97 | HTR1B (0.62) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8881179 | 0.96 | HTR1B (0.61) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8880624 | 0.95 | HTR1B (0.64) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8879194 | 0.92 | HTR1B (0.58) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8880172 | 0.90 | HTR1B (0.58) | HTR1BHTR1AHTR6MEN1LMNA | |
| SCHEMBL8879441 | 0.90 | HTR1B (0.58) | HTR1BHTR1AHTR6MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046525-A1 | 5-ALKOXY-TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR AGONISTS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-12-11 | — | — | WO | disclosed |
| US-5654431-A | EXHIBIT SELECTIVITY TOWARDS 5-HYDROXYTRYPTAMINE RECEPTORS OF BRAIN CELLS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-08-05 | — | — | US | disclosed |