Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14156408 | 0.85 | SLC6A4 (0.44) | SLC6A3SLC6A4SLC6A2CYP1A2 | |
| SCHEMBL26208919 | 0.83 | SLC6A4 (0.43) | SLC6A3SLC6A4SLC6A2CYP1A2 | |
| SCHEMBL7321869 | 0.80 | SLC6A4 (0.48) | SLC6A3SLC6A4SLC6A2CYP1A2 | |
| SCHEMBL21880254 | 0.78 | BCHE (0.35) | GAAMAPTNPSR1NOX1SLC6A3 | |
| SCHEMBL7322303 | 0.77 | P2RX1 (0.44) | GAAMAPTNPSR1NOX1SLC6A3 | |
| SCHEMBL22169961 | 0.77 | POLB (0.31) | — | |
| SCHEMBL18386007 | 0.76 | SLC6A4 (0.45) | MAPTSLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14970793 | 0.76 | SLC6A2 (0.43) | MAPTSLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7310248 | 0.75 | BCHE (0.39) | GAAMAPTNPSR1NOX1SLC6A3 | |
| SCHEMBL26403403 | 0.75 | SLC6A4 (0.43) | MAPTSLC6A3SLC6A4SLC6A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275523-A1 | METHODS AND KITS FOR ANALYZING POLYNUCLEOTIDE SEQUENCES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-11-10 | — | — | US | disclosed |
| US-7981604-B2 | Methods and kits for analyzing polynucleotide sequences | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-07-19 | — | — | US | disclosed |
| EP-2248911-A1 | Methods and kits for analyzing polynucleotide sequences | Helicos Biosciences Corporation (US) | 2010-11-10 | — | — | EP | disclosed |
| EP-1716254-B1 | METHODS FOR ANALYZING POLYNUCLEOTIDE SEQUENCES | HELICOS BIOSCIENCES CORP (US) | 2010-04-07 | — | — | EP | disclosed |
| EP-1716254-A2 | METHODS AND KITS FOR ANALYZING POLYNUCLEOTIDE SEQUENCES | Helicos Biosciences Corporation (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060019267-A1 | Methods and kits for analyzing polynucleotide sequences | HELICOS BIOSCIENCES CORPORATION | 2006-01-26 | — | — | US | disclosed |
| WO-2005080605-A2 | METHODS AND KITS FOR ANALYZING POLYNUCLEOTIDE SEQUENCES | HELICOS BIOSCIENCES CORPORATION (US) | 2005-09-01 | — | — | WO | disclosed |