Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007384 | 0.89 | CHRM1 (0.34) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL8880878 | 0.76 | PTPRC (0.35) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL8893107 | 0.68 | PTPRC (0.49) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL13698354 | 0.64 | PTPRC (0.50) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL8881300 | 0.63 | MEN1 (0.38) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL7282 | 0.62 | VHL (0.57) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL11172085 | 0.61 | CA1 (0.47) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL12393588 | 0.59 | PTPRC (0.62) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL8062143 | 0.59 | PTPRC (0.62) | PTPRCS100A4TDP1ALDH1A1CYP3A4 | |
| SCHEMBL31069945 | 0.59 | PTPRC (0.44) | PTPRCS100A4TDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | claimed |
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | disclosed |