Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968780 | 0.94 | KMT2A (0.51) | MEN1KMT2ACTSAEGLN2FTO | |
| SCHEMBL8883325 | 0.93 | MEN1 (0.50) | MEN1KMT2ACTSAEGLN2FTO | |
| SCHEMBL964994 | 0.92 | PTPN1 (0.49) | MEN1KMT2ACTSAPTPN1HTT | |
| SCHEMBL969853 | 0.92 | PTPN1 (0.49) | MEN1KMT2ACTSAPTPN1HTT | |
| SCHEMBL7206287 | 0.92 | PTPN1 (0.49) | MEN1KMT2ACTSAPTPN1HTT | |
| SCHEMBL8882071 | 0.92 | PTPN1 (0.49) | MEN1KMT2ACTSAPTPN1HTT | |
| SCHEMBL964996 | 0.92 | PTPN1 (0.49) | MEN1KMT2ACTSAPTPN1HTT | |
| SCHEMBL8883981 | 0.92 | PTPN1 (0.49) | MEN1KMT2ACTSAPTPN1HTT | |
| Hydrochloric Acid SCHEMBL966022 | 0.91 | PTPN1 (0.48) | MEN1KMT2ACTSAPTPN1HTT | |
| SCHEMBL8135880 | 0.85 | EGLN2 (0.62) | EGLN2FTOHTTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |