SCHEMBL888336

SCHEMBL888336

CO[Si](NC(C)(C)C)(OC)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4205790 0.70
SCHEMBL888426 0.69
SCHEMBL721357 0.69
SCHEMBL4209585 0.67
SCHEMBL17975878 0.67
SCHEMBL4208275 0.67
SCHEMBL3011889 0.63
SCHEMBL4204896 0.62 TSHR (0.33)
SCHEMBL4209670 0.61
SCHEMBL3008563 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2374821-B1 MANUFACTURING METHOD OF SOLID CATALYST COMPONENT AND OF CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2015-05-06 EP disclosed
US-8546290-B2 Solid catalyst component for olefin polymerization, manufacturing method, and catalyst and olefin polymer manufacturing method TOHO TITANIUM CO., LTD. (JP) 2013-10-01 US disclosed
US-20110269926-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD TOHO TITANIUM CO., LTD. (JP) 2011-11-03 US disclosed
EP-2374821-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD Toho Titanium CO., LTD. (JP) 2011-10-12 EP disclosed
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
US-20090215817-A1 Novel Triazolopyridine Compounds for the Treatment of Inflammation PFIZER INC 2009-08-27 US disclosed
US-20090209577-A1 Novel Triazolopyridine Compounds PFIZER INC. (US) 2009-08-20 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed