Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883299 | 1.00 | MEN1 (0.51) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8882066 | 1.00 | MEN1 (0.51) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8882411 | 1.00 | MEN1 (0.51) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8885314 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMPD1 | |
| SCHEMBL8881207 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8883432 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8885660 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8884846 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8882676 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMPD1ESR1CYP3A4 | |
| SCHEMBL8885561 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMPD1ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |