Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824661 | 0.81 | KMT2A (0.47) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL7819216 | 0.77 | KMT2A (0.55) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL9369081 | 0.76 | KMT2A (0.54) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL26623920 | 0.72 | KMT2A (0.55) | KMT2APDK2LMNATSHRALDH1A1 | |
| SCHEMBL26627265 | 0.71 | KMT2A (0.54) | KMT2APDK2LMNATSHRALDH1A1 | |
| SCHEMBL12474134 | 0.70 | KMT2A (0.53) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL28525712 | 0.70 | KMT2A (0.53) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL30492227 | 0.69 | KMT2A (0.64) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL13066502 | 0.69 | KMT2A (0.64) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL4444645 | 0.68 | KMT2A (0.67) | KMT2ALMNATSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
| US-5618812-A | GASTRIN ANTAGONISTS; GASTROINTESTINAL DISORDERS | MERCK SHARP & DOHME, LTD. (GB) | 1997-04-08 | — | — | US | disclosed |