Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027216 | 0.95 | TACR2 (0.51) | TACR2TACR1MEN1KMT2AOPRD1 | |
| SCHEMBL8592345 | 0.91 | TACR2 (0.65) | TACR2TACR1HRH1 | |
| SCHEMBL8883479 | 0.91 | TACR2 (0.65) | TACR2TACR1HRH1 | |
| SCHEMBL8882429 | 0.91 | TACR2 (0.65) | TACR2TACR1HRH1 | |
| SCHEMBL8882649 | 0.90 | TACR2 (0.53) | TACR2TACR1HRH1 | |
| SCHEMBL8882191 | 0.89 | TACR2 (0.54) | TACR2TACR1HRH1 | |
| SCHEMBL8884449 | 0.89 | TACR2 (0.55) | TACR2TACR1MEN1KMT2AHRH1 | |
| SCHEMBL8885397 | 0.89 | TACR2 (0.53) | TACR2TACR1HRH1 | |
| SCHEMBL8885371 | 0.89 | TACR2 (0.53) | TACR2TACR1HRH1 | |
| SCHEMBL8885359 | 0.88 | TACR2 (0.54) | TACR2TACR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607947-A | Pyrrolidinyl tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |