Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.85 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188315 | 0.92 | TACR1 (1.00) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL9321839 | 0.92 | TACR1 (1.00) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL28861521 | 0.92 | TACR1 (1.00) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL6135549 | 0.92 | TACR1 (1.00) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL9321845 | 0.92 | TACR1 (1.00) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL28229229 | 0.92 | TACR1 (1.00) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL6135372 | 0.92 | TACR1 (1.00) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL8795751 | 0.85 | TACR1 (0.69) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL8795788 | 0.85 | TACR1 (0.89) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL9324171 | 0.85 | TACR1 (0.86) | TACR1NPC1MTORRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604252-A | Azanorbornane derivatives | PFIZER INC. (US) | 1997-02-18 | — | — | US | disclosed |