Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.67 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.67 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.67 |
| ▸ | P2RY2 | P41231 | 11/20 | 0.50 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17198507 | 0.91 | SLC28A1 (0.74) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL20610932 | 0.91 | SLC28A1 (0.74) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL17198476 | 0.91 | SLC28A1 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL31543004 | 0.91 | SLC28A1 (0.74) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL9144523 | 0.90 | SLC28A1 (0.72) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL8887620 | 0.86 | SLC28A1 (0.67) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL8888068 | 0.86 | SLC28A1 (0.67) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL8889866 | 0.86 | SLC28A1 (0.67) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL21418727 | 0.85 | SLC28A1 (0.66) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL17198342 | 0.85 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597824-A | VIRICIDES | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |
| US-5420276-A | Ring contraction via diazoketone intermediate, active against herpes | ABBOTT LABORATORIES (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0433898-A2 | Analogs of oxetanyl purines and pyrimidines | ABBOTT LABORATORIES (US) | 1991-06-26 | — | — | EP | disclosed |