Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17372031 | 0.80 | SLC28A1 (0.49) | P2RY2P2RY4POLA1SLC28A1SLC28A2 | |
| SCHEMBL17372034 | 0.80 | SLC28A1 (0.49) | P2RY2P2RY4POLA1SLC28A1SLC28A2 | |
| SCHEMBL6714493 | 0.80 | SLC28A1 (0.49) | P2RY2P2RY4POLA1SLC28A1SLC28A2 | |
| SCHEMBL29324916 | 0.78 | NT5E (0.51) | POLBMEN1USP2KMT2ANT5E | |
| SCHEMBL19534595 | 0.78 | P2RY2 (0.60) | POLBMEN1USP2KMT2ANT5E | |
| SCHEMBL4328120 | 0.78 | CYP3A4 (0.41) | POLBMEN1USP2KMT2ANT5E | |
| SCHEMBL4268285 | 0.78 | CYP3A4 (0.41) | POLBMEN1USP2KMT2ANT5E | |
| SCHEMBL4333827 | 0.78 | CYP3A4 (0.41) | POLBMEN1USP2KMT2ANT5E | |
| SCHEMBL4325664 | 0.78 | CYP3A4 (0.41) | POLBMEN1USP2KMT2ANT5E | |
| SCHEMBL4336395 | 0.78 | CYP3A4 (0.41) | POLBMEN1USP2KMT2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597824-A | VIRICIDES | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |
| US-5420276-A | Ring contraction via diazoketone intermediate, active against herpes | ABBOTT LABORATORIES (US) | 1995-05-30 | — | — | US | disclosed |