Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.77 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | LTA4H | P09960 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.65 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.63 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20834076 | 1.00 | FFAR1 (0.77) | FFAR1FFAR4MAPTRXFP1LTA4H | |
| SCHEMBL28441593 | 0.98 | FFAR1 (0.79) | FFAR1FFAR4MAPTRXFP1LTA4H | |
| SCHEMBL7905578 | 0.94 | FFAR1 (0.82) | FFAR1FFAR4LTA4HEPHX2ALOX5 | |
| Azelaic Acid SCHEMBL21879788 | 0.91 | FFAR1 (0.73) | FFAR1FFAR4MAPTRXFP1LTA4H | |
| Pimelic Acid SCHEMBL21879736 | 0.91 | FFAR1 (0.73) | FFAR1FFAR4MAPTRXFP1LTA4H | |
| SCHEMBL1171526 | 0.88 | FFAR1 (0.67) | FFAR1FFAR4ALOX5MGLL | |
| SCHEMBL1171933 | 0.88 | FFAR1 (0.67) | FFAR1FFAR4ALOX5MGLL | |
| SCHEMBL1799635 | 0.88 | FFAR1 (0.67) | FFAR1FFAR4ALOX5MGLL | |
| SCHEMBL1744939 | 0.87 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| Benzyloxyphenylpropanoic Acid SCHEMBL1134648 | 0.87 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |