SCHEMBL88894

SCHEMBL88894

c1ccc2c(c1)NCCO2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.55
ALDH1A1 P00352 1/20 0.55
MAPT P10636 1/20 0.55
HSD17B10 Q99714 1/20 0.55
ITGB2 P05107 1/20 0.50
ICAM1 P05362 1/20 0.50
ITGAL P20701 1/20 0.50
LMNA P02545 2/20 0.44
CRHBP P24387 2/20 0.44
CRHR2 Q13324 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTT P42858 1/20 0.44
KEAP1 Q14145 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
BRD4 O60885 1/20 0.42
GRM5 P41594 3/20 0.40
PDE3B Q13370 1/20 0.40
PDE3A Q14432 1/20 0.40
ALOX5 P09917 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8942627 1.00 GAA (0.55) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL871099 1.00 GAA (0.55) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL56313 1.00 GAA (0.55) GAAALDH1A1MAPTHSD17B10ITGB2
Hydrochloric Acid SCHEMBL27373511 0.98 GAA (0.53) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL6046277 0.96 ITGB2 (0.58) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL8521592 0.88 SMN1; SMN2 (0.59) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL2316918 0.88 SMN1; SMN2 (0.59) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL15479701 0.88 SMN1; SMN2 (0.59) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL2315177 0.88 SMN1; SMN2 (0.59) GAAALDH1A1MAPTHSD17B10ITGB2
SCHEMBL16738555 0.87 GAA (0.45) GAAALDH1A1MAPTHSD17B10ITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17630 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP claimed
CN-122094941-A Novel azido formation of 6-hydroxy-benzomorpholine (3, 4-dihydro-2H-1, 4-benzoxazin-6-ol) 2026-05-26 CN claimed
WO-2026103601-A1 RU-NI BIMETALLIC CATALYST FOR SELECTIVE HYDROGENATION OF QUINOLINE ORGANIC HYDROGEN STORAGE CARRIER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 天府永兴实验室 2026-05-21 WO claimed
CN-118005569-B 6-Aminoquinoxaline compound and preparation method and application thereof 华南理工大学 2026-05-19 CN claimed
CN-122005558-A Compound serving as AKR1C3 inhibitor as well as preparation method and application thereof 广州医科大学 2026-05-12 CN claimed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP claimed
EP-4663723-A1 LUBRICANT COMPOSITION, LUBRICANT COMPOSITION ADDITIVE, AND USES OF LUBRICANT COMPOSITION NEOL Copper Technologies Limited (GB) 2025-12-17 EP claimed
US-20250353858-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-20 US claimed
EP-2958562-B1 ANTIDIABETIC BICYCLIC COMPOUNDS MERCK SHARP & DOHME LLC (US) 2025-09-10 EP claimed
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
US-4233398-A Process for the hardening of photographic layers utilizing fast acting hardener and polysaccharide AGFA-GEVAERT, A.G. (DE) 1980-11-11 US claimed
US-4180663-A FORMYLATION OF AROMATIC AMINE, CONDENSATION WITH MALONONITRILE GENERATED IN SITU FROM CYANOACETAMIDE EASTMAN KODAK COMPANY (US) 1979-12-25 US claimed
EP-0005652-A2 Electrophoretic migration imaging process and dispersion EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-11-28 EP claimed
US-4172944-A Water insoluble styryl dyestuffs having hetero-aryl methylene substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-10-30 US claimed
US-4166740-A CYANINE DYES EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed
US-4165985-A PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS EASTMAN KODAK COMPANY (US) 1979-08-28 US claimed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US claimed
EP-0000596-A1 Electrically photosensitive particles for electrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
US-4055542-A PEROXIDE THREE BOND CO., LTD. (JA) 1977-10-25 US claimed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US claimed