Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888843 | 0.85 | MEN1 (0.53) | PDE4BCSF1RFGFR1FLT1KDR | |
| SCHEMBL8890041 | 0.84 | CSF1R (0.46) | PDE4BSMN1; SMN2CSF1RFGFR1FLT1 | |
| SCHEMBL8890259 | 0.83 | FLT1 (0.48) | PDE4BSMN1; SMN2CSF1RFGFR1FLT1 | |
| SCHEMBL8888266 | 0.81 | CSF1R (0.66) | SMN1; SMN2CSF1RFGFR1FLT1KDR | |
| SCHEMBL3032899 | 0.80 | CSF1R (0.69) | PDE4BSMN1; SMN2CSF1RFGFR1FLT1 | |
| SCHEMBL11862067 | 0.79 | CA1 (0.56) | PDE4BSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL8887875 | 0.78 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2AL3MBTL1ADORA3 | |
| SCHEMBL4708098 | 0.78 | PDE4B (0.54) | PDE4BSMN1; SMN2CSF1RFGFR1FLT1 | |
| SCHEMBL11541106 | 0.78 | PTGDR2 (0.54) | SMN1; SMN2MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL3033412 | 0.76 | PDE4B (0.55) | PDE4BSMN1; SMN2CSF1RFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |