Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62944 | 0.98 | TSHR (0.46) | TSHRBCL2L1BADSIGMAR1HPGD | |
| SCHEMBL152117 | 0.98 | TSHR (0.46) | TSHRBCL2L1BADSIGMAR1HPGD | |
| SCHEMBL151022 | 0.98 | TSHR (0.46) | TSHRBCL2L1BADSIGMAR1HPGD | |
| SCHEMBL24682 | 0.95 | — | — | |
| SCHEMBL34907 | 0.85 | — | — | |
| SCHEMBL2885325 | 0.78 | TSHR (0.50) | TSHRBCL2L1BADSIGMAR1HPGD | |
| SCHEMBL10471250 | 0.77 | CYP2A6 (0.47) | TSHRHPGDL3MBTL1CYP2A6MAOA | |
| SCHEMBL520050 | 0.76 | — | — | |
| SCHEMBL12520890 | 0.74 | TSHR (0.31) | TSHR | |
| SCHEMBL5420509 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8603 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | claimed |
| CN-117813306-A | Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use | 上海科州药物研发有限公司 | 2024-04-02 | — | — | CN | claimed |
| EP-4301816-A1 | COATING COMPOSITIONS COMPRISING A POLYSULFIDE CORROSION INHIBITOR | PRC-Desoto International, Inc. (US) | 2024-01-10 | — | — | EP | claimed |
| CN-117377727-A | Coating composition comprising polysulfide corrosion inhibitor | PRC-迪索托国际公司 | 2024-01-09 | — | — | CN | claimed |
| WO-2024005197-A1 | SOLID DISPERSION, PHARMACEUTICAL PREPARATION CONTAINING SOLID DISPERSION, AND METHODS RESPECTIVELY FOR PRODUCING THESE PRODUCTS | 日本新薬株式会社 | 2024-01-04 | — | — | WO | claimed |
| CN-117304205-A | Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-12-29 | — | — | CN | claimed |
| CN-117304204-A | Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-12-29 | — | — | CN | claimed |
| CN-111757884-B | Substituted macrocyclic indole derivatives | 拜耳股份公司 | 2023-12-19 | — | — | CN | claimed |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | claimed |
| US-4066759-A | ANTITHROMBOTIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-01-03 | — | — | US | claimed |
| US-4061653-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | claimed |
| US-4049645-A | ANTITHROMBOTIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-09-20 | — | — | US | claimed |
| US-4036955-A | TREATMENT OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-07-19 | — | — | US | claimed |
| US-3993766-A | Substituted 2-amino-Δ2 -thiazoline derivatives as acaricidal agents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | claimed |
| US-3978077-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (GB) | 1976-08-31 | — | — | US | claimed |
| US-3973033-A | Compositions and methods for producing a vasodilatory effect with a naphthyl tetrahydrofurfuryl amino-ester | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1976-08-03 | — | — | US | claimed |
| US-3959332-A | N-(2-NITRO-4-ARYLOXYSULFONYL-PHENYL)-ARYLENEDIAMINES, DYES | SANDOZ LTD. (CH) | 1976-05-25 | — | — | US | claimed |
| US-3956335-A | HYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | claimed |
| US-3935250-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | claimed |