Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.31 |
| ▸ | FEN1 | P39748 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891459 | 0.73 | GAA (0.39) | MAPTGAAALDH1A1HPGDLMNA | |
| SCHEMBL8891610 | 0.69 | MAPT (0.35) | MAPTGAATSHR | |
| Dimethylamine SCHEMBL8892607 | 0.68 | GAA (0.36) | MAPTGAAALDH1A1KDM4ELMNA | |
| SCHEMBL8893140 | 0.64 | MAPT (0.34) | MAPTGAAALDH1A1HPGDKDM4E | |
| SCHEMBL8892604 | 0.64 | GAA (0.33) | MAPTGAA | |
| SCHEMBL20157365 | 0.62 | MAPT (0.42) | MAPTGAAALDH1A1HPGDLMNA | |
| SCHEMBL5154526 | 0.61 | — | — | |
| SCHEMBL12179246 | 0.60 | — | — | |
| SCHEMBL27562671 | 0.60 | GAA (0.47) | GAAALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL16075161 | 0.59 | GAA (0.57) | MAPTGAAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |