Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 9/20 | 0.47 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889924 | 0.98 | TDP1 (0.57) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL14009212 | 0.97 | TDP1 (0.59) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL8891160 | 0.94 | TDP1 (0.59) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL8891384 | 0.94 | TDP1 (0.59) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL8891833 | 0.93 | TDP1 (0.62) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL12808793 | 0.91 | TDP1 (0.59) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL15613415 | 0.91 | TDP1 (0.58) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL7414603 | 0.91 | TDP1 (0.58) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL27296655 | 0.91 | TDP1 (0.66) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL29559060 | 0.90 | TDP1 (0.55) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027179-A2 | ANTIRETROVIRAL BASES | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | disclosed |