Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.89 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | DRD4 | P21917 | 5/20 | 0.66 |
| ▸ | DRD2 | P14416 | 4/20 | 0.64 |
| ▸ | DRD3 | P35462 | 4/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653218 | 0.94 | CCR3 (1.00) | CCR3OPRL1POLBDRD4DRD2 | |
| Bromide SCHEMBL28537686 | 0.92 | CCR3 (0.94) | CCR3OPRL1POLBDRD4DRD2 | |
| SCHEMBL28525891 | 0.89 | CCR3 (0.89) | CCR3OPRL1POLBDRD4DRD2 | |
| SCHEMBL29087358 | 0.86 | CCR3 (0.83) | CCR3OPRL1POLBDRD4DRD2 | |
| SCHEMBL1411499 | 0.85 | OPRL1 (1.00) | CCR3OPRL1POLBDRD4OPRM1 | |
| SCHEMBL3890625 | 0.82 | OPRL1 (0.82) | CCR3OPRL1POLBDRD4DRD2 | |
| SCHEMBL27582059 | 0.82 | CCR3 (0.82) | CCR3OPRL1POLBDRD2DRD3 | |
| SCHEMBL6496650 | 0.81 | CCR3 (0.74) | CCR3OPRL1POLBDRD4DRD2 | |
| SCHEMBL6110923 | 0.81 | OPRL1 (0.79) | CCR3OPRL1POLBDRD4DRD2 | |
| SCHEMBL15530820 | 0.81 | OPRL1 (0.79) | CCR3OPRL1POLBDRD4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |