Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A15 | Q9H2J7 | 10/20 | 0.75 |
| ▸ | PTAFR | P25105 | 9/20 | 0.74 |
| ▸ | HRH1 | P35367 | 6/20 | 0.58 |
| ▸ | FNTA | P49354 | 3/20 | 0.57 |
| ▸ | FNTB | P49356 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893263 | 0.89 | SLC6A15 (0.79) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL8890630 | 0.89 | PTAFR (0.75) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL8889945 | 0.87 | SLC6A15 (0.78) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL8889615 | 0.86 | SLC6A15 (0.81) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL8878586 | 0.86 | PTAFR (1.00) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL8890300 | 0.85 | SLC6A15 (0.86) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL8877554 | 0.85 | SLC6A15 (1.00) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL9591418 | 0.84 | SLC6A15 (0.77) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL9592075 | 0.84 | SLC6A15 (0.77) | SLC6A15PTAFRHRH1FNTAFNTB | |
| SCHEMBL9591552 | 0.83 | SLC6A15 (0.75) | SLC6A15PTAFRHRH1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665726-A | ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0685476-A1 | Benzo(5,6)cycloheptapyridines, compositions and methods of use | SCHERING CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5438062-A | Antiallergens, antiinflammatory agents | SCHERING CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0270818-B1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORP (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0330673-A1 | BENZO 5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4826853-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0270818-A1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988003138-A1 | BENZO[5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |