Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.44 |
| ▸ | XIAP | P98170 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7412390 | 0.99 | F2 (0.53) | F2PLGPRSS1OPRM1OPRK1 | |
| SCHEMBL7446078 | 0.92 | F2 (0.56) | F2PLGPRSS1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7414568 | 0.91 | F2 (0.55) | F2PLGPRSS1OPRM1OPRK1 | |
| SCHEMBL7451955 | 0.91 | F2 (0.55) | F2PLGPRSS1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7414559 | 0.91 | F2 (0.54) | F2PLGPRSS1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7413020 | 0.90 | F2 (0.54) | F2PLGPRSS1OPRM1OPRK1 | |
| SCHEMBL7441266 | 0.89 | F2 (0.53) | F2PLGPRSS1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7419175 | 0.89 | F2 (0.54) | F2PLGPRSS1OPRM1OPRK1 | |
| Efegatran SCHEMBL564291 | 0.89 | F2 (0.56) | F2PLGPRSS1OPRM1OPRK1 | |
| Efegatran SCHEMBL7273879 | 0.89 | F2 (0.56) | F2PLGPRSS1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602101-A | THROMBIN INHIBITORS, ANTICOAGULANTS | ELI LILLY AND COMPANY (US) | 1997-02-11 | — | — | US | claimed |