SCHEMBL8892447

SCHEMBL8892447

N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccn1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 16/20 0.80
CCR3 P51677 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Berlex Compound SCHEMBL8891715 0.89 CCR1 (1.00) CCR1CCR3
Berlex Compound SCHEMBL29401934 0.88 CCR1 (0.98) CCR1CCR3
SCHEMBL9105312 0.86 CCR1 (1.00) CCR1CCR3
SCHEMBL9104114 0.85 CCR1 (1.00) CCR1CCR3
SCHEMBL2312804 0.83 CCR1 (1.00) CCR1CCR3
Hydrochloric Acid SCHEMBL11629523 0.82 CCR1 (0.98) CCR1CCR3
SCHEMBL9107132 0.82 KCNA3 (0.86) CCR1CCR3
Hydrochloric Acid SCHEMBL8909224 0.81 CCR1 (0.80) CCR1CCR3
SCHEMBL9109738 0.81 CCR1 (1.00) CCR1CCR3
SCHEMBL9106148 0.80 CCR1 (0.82) CCR1CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997024325-A1 DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-07-10 WO disclosed