Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.60 |
| ▸ | AQP1 | P29972 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | NPY4R | P50391 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890250 | 0.95 | NPY5R (0.66) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL2636281 | 0.92 | NPY5R (0.64) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8906965 | 0.91 | NPY5R (0.62) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2675360 | 0.91 | NPY5R (0.62) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL8908378 | 0.84 | NPY5R (0.64) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL2804110 | 0.83 | NPY5R (0.62) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL2804108 | 0.83 | NPY5R (0.62) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL8899497 | 0.83 | NPY5R (0.62) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL8892672 | 0.82 | NPY5R (0.56) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL6674509 | 0.82 | NPY5R (0.60) | NPY5RAQP1ADRA2AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |