SCHEMBL8892750

SCHEMBL8892750

C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 11/20 0.61
DPP7 Q9UHL4 10/20 0.61
PREP P48147 4/20 0.61
FAP Q12884 7/20 0.48
DPP8 Q6V1X1 6/20 0.48
DPP9 Q86TI2 5/20 0.48
PITRM1 Q5JRX3 1/20 0.48
ACE P12821 6/20 0.44
REN P00797 3/20 0.44
KDM4E B2RXH2 1/20 0.44
F2 P00734 1/20 0.44
LMNA P02545 1/20 0.44
LTA4H P09960 1/20 0.44
MAPT P10636 1/20 0.44
PEPD P12955 1/20 0.44
ALOX15 P16050 1/20 0.44
PTGS1 P23219 1/20 0.44
HTR2A P28223 1/20 0.44
PTGS2 P35354 1/20 0.44
HRH1 P35367 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892746 1.00 DPP4 (0.61) DPP4DPP7PREPFAPDPP8
SCHEMBL19167069 1.00 DPP4 (0.61) DPP4DPP7PREPFAPDPP8
SCHEMBL21549057 0.94 DPP4 (0.56) DPP4DPP7PREPFAPDPP8
SCHEMBL16695995 0.94 DPP4 (0.56) DPP4DPP7PREPFAPDPP8
SCHEMBL23045900 0.89 DPP4 (0.60) DPP4DPP7PREPFAPDPP8
SCHEMBL12404687 0.89 DPP4 (0.60) DPP4DPP7PREPFAPDPP8
SCHEMBL30797970 0.89 DPP4 (0.60) DPP4DPP7PREPFAPDPP8
SCHEMBL34461073 0.89 DPP4 (0.60) DPP4DPP7PREPFAPDPP8
SCHEMBL19165611 0.87 DPP4 (0.61) DPP4DPP7PREPFAPDPP8
SCHEMBL22542490 0.87 DPP4 (0.61) DPP4DPP7PREPFAPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024189611-A1 STABILIZED ANALOGUES OF CALCITONIN YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-09-19 WO claimed
US-5599791-A BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA GRUPPO LEPETIT SPA (IT) 1997-02-04 US claimed
WO-1992012172-A9 AMIDES OF ANTIBIOTIC GE 2270 FACTORS 1996-04-04 WO claimed
EP-0565567-B1 AMIDES OF ANTIBIOTIC GE 2270 FACTORS LEPETIT SPA (IT) 1995-01-18 EP claimed
EP-0565567-A1 AMIDES OF ANTIBIOTIC GE 2270 FACTORS. LEPETIT SPA (IT) 1993-10-20 EP claimed
WO-1992012172-A1 AMIDES OF ANTIBIOTIC GE 2270 FACTORS GRUPPO LEPETIT S.P.A. (IT) 1992-07-23 WO claimed
EP-0494078-A1 Amides of antibiotic ge 2270 factors GRUPPO LEPETIT S.p.A. (IT) 1992-07-08 EP claimed
US-12497644-B2 Subtilisin variants and their use Fresenius Kabi Ipsum S.R.L. (IT) 2025-12-16 US disclosed
US-20250320471-A1 Method for Producing Compounds, Method for Producing Compound Library, Compound Library, and Screening Method UNIV TOKYO (JP) 2025-10-16 US disclosed
US-20250177503-A1 COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-06-05 US disclosed
US-5599791-A BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA GRUPPO LEPETIT SPA (IT) 1997-02-04 US disclosed
WO-1992012172-A9 AMIDES OF ANTIBIOTIC GE 2270 FACTORS 1996-04-04 WO disclosed
EP-0565567-B1 AMIDES OF ANTIBIOTIC GE 2270 FACTORS LEPETIT SPA (IT) 1995-01-18 EP disclosed
EP-0565567-A1 AMIDES OF ANTIBIOTIC GE 2270 FACTORS. LEPETIT SPA (IT) 1993-10-20 EP disclosed
WO-1992012172-A1 AMIDES OF ANTIBIOTIC GE 2270 FACTORS GRUPPO LEPETIT S.P.A. (IT) 1992-07-23 WO disclosed
EP-0494078-A1 Amides of antibiotic ge 2270 factors GRUPPO LEPETIT S.p.A. (IT) 1992-07-08 EP disclosed