Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3645265 | 0.77 | — | — | |
| SCHEMBL8500841 | 0.74 | — | — | |
| SCHEMBL8401874 | 0.66 | — | — | |
| SCHEMBL6455211 | 0.61 | — | — | |
| SCHEMBL9188946 | 0.60 | HTR2A (0.48) | HTR2A | |
| SCHEMBL9188953 | 0.60 | HTR2A (0.48) | HTR2A | |
| SCHEMBL7757592 | 0.59 | KDM4E (0.33) | — | |
| SCHEMBL19586953 | 0.59 | HTR2A (1.00) | HTR2A | |
| SCHEMBL19586584 | 0.59 | HTR2A (1.00) | HTR2A | |
| SCHEMBL19586755 | 0.59 | HTR2A (1.00) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997040013-A1 | METHOD FOR PREPARATION OF COMPOUNDS USEFUL FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1997-10-30 | — | — | WO | disclosed |