Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238225 | 0.81 | CYP11B1 (0.36) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL25307807 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL27579878 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL3516047 | 0.79 | CYP11B1 (0.41) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL10815632 | 0.77 | CYP11B1 (0.35) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL9234834 | 0.77 | HDAC3 (0.37) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL8481796 | 0.76 | CYP11B1 (0.40) | CYP11B1CYP11B2HDAC3HDAC6BMP1 | |
| SCHEMBL1765841 | 0.76 | CYP11B1 (0.40) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL6613495 | 0.76 | HDAC3 (0.40) | CYP11B1CYP11B2HDAC3HDAC6NOS1 | |
| SCHEMBL9235495 | 0.76 | CYP11B1 (0.37) | CYP11B1CYP11B2HDAC3HDAC6BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |