Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL10883274 | 0.95 | PTPN1 (0.37) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| SCHEMBL49498 | 0.95 | PTPRC (0.39) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| Ammonia Solution, Strong SCHEMBL27769335 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| Bromide SCHEMBL28112337 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| Fluoride SCHEMBL27765937 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| Ammonia Solution, Strong SCHEMBL27759355 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| Methane SCHEMBL29033872 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| SCHEMBL678826 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| Benzene SCHEMBL5334270 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD | |
| SCHEMBL28084319 | 0.93 | PTPN1 (0.38) | PTPN1IDO1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1160309-C | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | �ճ�˹�������³˹��˾ | 2004-08-04 | — | — | CN | disclosed |
| CN-1220660-A | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | HOECHST MARION ROUSSEL INC (US) | 1999-06-23 | — | — | CN | disclosed |
| WO-1997004770-A1 | 2-(FLUORENONYL)-CARBAPENEMS, COMPOSITIONS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-13 | — | — | WO | disclosed |
| US-5451579-A | 1-β-methyl-carbapenem, compositions containing same and methods of use | MERCK & CO., INC. (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1995021841-A1 | 1-β-METHYL-CARBAPENEM, COMPOSITIONS CONTAINING SAME AND METHODS OF USE | MERCK & CO., INC. (US) | 1995-08-17 | — | — | WO | disclosed |