Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 8/20 | 0.39 |
| ▸ | UGCG | Q16739 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | AGL | P35573 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLB1 | P16278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274980 | 0.95 | ATM (0.46) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL9274978 | 0.95 | ATM (0.46) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL10853886 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL455059 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL28867212 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL8164154 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL8163625 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL452991 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL8155446 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 | |
| SCHEMBL8875794 | 0.93 | ATM (0.45) | ATMGBA2UGCGGAAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665371-A | SIDE EFFECT REDUCTION | HOERRMANN WILHELM (DE) | 1997-09-09 | — | — | US | claimed |
| CN-108484720-A | A kind of antihypertensive active peptide Orn-Pro-Hyp and application and pharmaceutical composition | 南京大学 | 2018-09-04 | — | — | CN | disclosed |
| WO-2014127052-A1 | PERFLUORO-TERT-BUTYL HYDROXYPROLINE | ZONDLO NEAL (US) | 2014-08-21 | — | — | WO | disclosed |