Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894771 | 0.88 | FNTA (0.46) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL8895417 | 0.87 | FNTA (0.46) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL8894055 | 0.85 | TACR1 (0.46) | ALDH1A1KMT2AMEN1FNTAFNTB | |
| SCHEMBL9142783 | 0.84 | FNTA (0.60) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL8783447 | 0.82 | FNTA (0.53) | MAPTKMT2AMEN1FNTAFNTB | |
| SCHEMBL8788673 | 0.81 | FNTA (0.52) | ALDH1A1MAPTKMT2AMEN1FNTA | |
| SCHEMBL9139914 | 0.81 | FNTA (0.52) | ALDH1A1MAPTKMT2AMEN1FNTA | |
| SCHEMBL8894203 | 0.80 | TACR1 (0.51) | MAPTKMT2AMEN1FNTAFNTB | |
| SCHEMBL8894524 | 0.80 | TACR1 (0.51) | MAPTKMT2AMEN1FNTAFNTB | |
| SCHEMBL8895688 | 0.80 | FNTA (0.51) | MAPTKMT2AMEN1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631279-A | ANTAGONISTS OF NEUROKININ A | RHONE-POULENC RORER, S.A. (FR) | 1997-05-20 | — | — | US | disclosed |