SCHEMBL8894552

SCHEMBL8894552

CN(C)CCOCCOC[C]=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
USP2 O75604 1/20 0.37
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRM3 P20309 1/20 0.35
CHRNA4 P43681 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
KDM4E B2RXH2 8/20 0.34
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 2/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892717 0.95
SCHEMBL3973874 0.80 CA12 (0.56) CA12CA1CA2CA9USP2
SCHEMBL2780260 0.80 MEN1 (0.32) MEN1KMT2A
SCHEMBL12918862 0.80 CA12 (0.56) CA12CA1CA2CA9USP2
Ammonia Solution, Strong SCHEMBL17238502 0.77 CA12 (0.54) CA12CA1CA2CA9USP2
SCHEMBL15091 0.77 CA12 (0.52) CA12CA1CA2CA9USP2
Water SCHEMBL2217898 0.74 CA12 (0.50) CA12CA1CA2CA9USP2
SCHEMBL31696969 0.74 CA12 (0.50) CA12CA1CA2CA9USP2
Hydrochloric Acid SCHEMBL473385 0.74 CA12 (0.50) CA12CA1CA2CA9USP2
Ammonia Solution, Strong SCHEMBL10349483 0.74 CA12 (0.50) CA12CA1CA2CA9USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643878-A TREATMENT OF RETROVIRAL DISEASES LIKE AIDS CIBA-GEIGY CORPORATION (US) 1997-07-01 US disclosed
EP-0618222-A2 Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid CIBA-GEIGY AG (CH) 1994-10-05 EP disclosed